Getting better results with a fluorogold slide plate
If you're currently prepping a fluorogold slide plate for your latest neuro-tracing study, you probably already know how fickle these samples can be if the conditions aren't just right. Fluorogold, or hydroxystilbamidine if you want to be formal about it, has been a staple in neuroscience labs for decades because it's incredibly reliable for retrograde labeling. But even the best tracer is only as good as the slide it's sitting on. When you're trying to map out axonal projections or figure out exactly which neurons are talking to each other, the way you handle that slide plate can make or break your imaging session. ...